Continuous manufacturing via hot-melt extrusion and scale up: regulatory matters
نویسندگان
چکیده
منابع مشابه
Continuous manufacturing via hot-melt extrusion and scale up: regulatory matters.
Currently, because globalization, the pharmaceutical industry is facing enormous challenges to comply with regulatory matters. Reduced patent life and overall decreased profitability of newly discovered drugs are also forcing the pharmaceutical industry to shorten the drug development time with maximum throughput. Therefore, continuous manufacturing (CM) processes via hot melt extrusion (HME) c...
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Hot-melt extrusion is one of the most widely applied processing technologies in the plastic, rubber and food industry. Today this technology has found its place in the array of pharmaceutical manufacturing operations. Melt extrusion process are currently applied in the pharmaceutical field for the manufacture of a variety of dosage forms and formulations such as granules, pellets, tablets, supp...
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ژورنال
عنوان ژورنال: Drug Discovery Today
سال: 2017
ISSN: 1359-6446
DOI: 10.1016/j.drudis.2016.11.007